Capadona Lab

Bio-Inspired Materials for Neural Interfacing

In the Capadona Lab, our research team focuses on developing a molecular level understanding of the neuroinflammatory response to implantable neuromoduluator/rehabilitative devices. Our belief is that a spatiotemporal understanding of the degenerative neuroinflammatory response to implanted devices must be implicit before targeted and responsive systems can be developed to integrate within neural tissue. Therefore, we have built a strong multi-disciplinary, multi-institutional team consisting of government, private-public, and academic-commercial partnerships across engineering, basic science, and clinical domains.

To accomplish this complex work, we are committed to actively developing and growing local, domestic, and international collaborations. We have an extensive list of contributing collaborators on research awards. Additionally, within the Cleveland research community, we have had and are currently maintaining funded grants as either a Co-I or a Co-PI with many collaborators. 

Recent News

  • August 1, 2019 - Welcomed Natalie Mueller, a new PhD student co-advised with Dr. Allison Hess-Dunning.
  • July 2019 - Dr. Capadona received VA Equipment funds to establish a 2- and 3-photon microscope.
  • July 1, 2019 - Dr. Andrew Shoffstall (postdoc 2015 - 2019) began a tenure-track position as assistant professor of biomedical engineering at Case Western Reserve University.
  • July 1, 2019 - Dr. Capadona was promoted to full professor.
  • June 1, 2019 - Welcomed Olivia Krebs and Danny Lam (co-advised with Dr. Andrew Shoffstall), new PhD students.
  • May 2019 - Dr. Hillary Bedell completed her PhD and began a career at GenomOncology.
  • May 2019 - Welcomed back Dhariyat Menendez, a new lab manager shared with the Shoffstall Lab.
  • April 2019 - NIH R01 from NINDS "Characterizing and mitigating the role of oxidative damage in microelectrode failure."
  • April 2019 - Dr. received VA RR&D Merit Review with Dr. Allison Hess-Dunning "Hybrid Drug-Eluting Microfluidic Neural Probe for Chronic Drug Infusion"
  • January 2019 - Dr. Capadona received VA Research Career Scientist Award.
  • July 2018 - Dr. received VA RR&D Merit Review with "Antioxidative Microelectrodes to Improve Neural Recording Performance." 
  • 2018 - Capadona Lab publishes 16 peer-reviewed manuscripts, reviews and book chapters in 2018.
  • Summer 2018 - Welcome 3 new PhD students: Youjoung Kim, George Hoeferlin, and Paul Gloth.
  • May 2018 - Dr. John Hermann completed his PhD and begins a post-doc position at the Cleveland Clinic.